Folic Acid for the Prevention of Neural Tube Defects
Committee on Genetics, PEDIATRICS Vol. 104 No. 2 August 1999, pp. 325-327
[for Professionals mainly]
Policy Statement - American Academy of Pediatrics (1993). "NTDs are among the most common birth defects that result in infant mortality and serious disability ..."

National Campaign on Folic Acid - Gate Page
Centers for Disease Control and Prevention, Department of Health and Human Services,

Folic Acid for Healthy Babies
National Center for Birth Defects and Developmental Disabilities, CDC, March 1999

Spinal Dysraphism
GeneCare Medical Genetics Center, May 25, 2004
Anencephalus or encephalocele and meningomyelocele or spina bifida ... with a Table of Recurrence Risks of NTD - GeneCare Corp.

Trends in Spina Bifida and Anencephalus in the United States, 1991-2001
T.J. Mathews, M.S., Division of Vital Statistics, National Center for Health Statistics, January 11, 2007
The rates for 1999, 2000, and 2001 were significantly lower than in 1997.  The rate of spina bifida in 2001 was 20.09 per 100,000 live births ...The rate of anencephalus in 2001 was 9.40 per 100,000 live births, significantly lower than in 1997.

National (Canada) Workshop
Folic Acid Alliance Ontario
[English] [French]
Primary Prevention of NTD, some Q & A.

Forma para solicitar materiales educativos...
CDC - Center for Disease Control, October 17, 2006
[Spanish]

Mortalidad por defectos del tubo neural en México, 1980-1997
Salud pública Méx vol.45 no.5 Cuernavaca Sep./Oct. 2003
[Spanish]
RESULTADOS: Durante el periodo la tasa bruta de mortalidad por defectos del tubo neural fue de 5.8 por 10 000 nacidos vivos. La anencefalia fue el tipo de defecto más frecuente (37.7%), seguida de la espina bífida sin hidrocefalia (31.6%). La tendencia nacional de la mortalidad por defectos del tubo neural fue ascendente entre 1980 y 1990 (porcentaje de cambio anual 7.5 IC 95% 6.5, 8.6) y descendente entre 1990-1997 (porcentaje de cambio anual -2.3 IC 95% -3.6, -0.9) ... CONCLUSIONES: Las altas tasas de mortalidad por defectos del tubo neural fueron debidas principalmente a la elevada frecuencia de las anencefalias ...

Frecuencia y algunos factores de riesgo de mortalidad en el estado de Hidalgo, México, por defectos de cierre del tubo neural
Salud pública Méx vol.44 no.5 Cuernavaca Sept.Oct. 2002
[Spanish]
Objetivo. Calcular el riesgo de muerte fetal secundaria a defectos del cierre del tubo neural y estimar factores asociados con este tipo de muertes en el estado de Hidalgo. Material y métodos. La información analizada en el año 2000 fue obtenida de los certificados de muerte fetal del periodo 1990-1995 en el estado de Hidalgo. Se utilizó un diseño de mortalidad proporcional, considerado como una variante del diseño de casos y controles. Los casos fueron aquellas muertes fetales secundarias a defectos del tubo neural y los controles las muertes fetales por otros motivos. Se utilizó ji cuadrada de Pearson para estimar las diferencias entre los casos y controles. Para el riesgo crudo de morir por defectos de cierre del tubo neural se empleó la razón de momios, y para el riesgo ajustado se usó la regresión logística no condicional ...

SPINA BIFIDA - MENINGOCELE

Spina Bifida
National Dissemination Center for Children with Disabilities, January 2004
[for Professionals mainly] [Support Group]
... incomplete closure in the spinal column ... three types ... occulta ... meningocele ... meningomyelocele ...

Meckel Gruber syndrome type 1
Johns Hopkins University, June 22, 2007
[for Professionals mainly]
Mostly for Medical Geneticists - 10 page authoritative review. "... called dysencephalia splachnocystica by Gruger ... "

Meckel Gruber syndrome type 2
Johns Hopkins University, January 03, 2007
[for Professionals mainly]
" ... clinical delineation .... been confusing "

Meckel Gruber - Dysencephalia Splanchnocystica Syndrome
Hans van der Slikke, MD, OBGYN.net, Sept. 1998
[for Professionals mainly]
Images - Prenatal Diagnosis
Elevated maternal and amniotic fluid alpha fetoprotein and
- occipital meningo-encephalocele
- microcephaly
- cleft palate
- polycystic kidneys
- polydactyly

Spina bifida fact sheet for Health Professionals
I.B.I.S. Birth Defects, 2005
[Ukrainian]
Clinical picture ... Complications ... Etiology ... Treatment ... Associated anomalies ... Prevention ... Prognosis ... Bibliography

Meckel Gruber Syndrome Fact Sheet for Health Professionals
I.B.I.S. Birth Defects, February 5, 2002
[Ukrainian]
Main diagnostic criteria ... Clinical picture ... Manifestation age ... Differential diagnosis ... Bibliography
 

HYDROCEPHALUS - ARNOLD CHIARI - ALLIED DISORDERS

Hydrocephalus, Syringomyelia ...
Neurosurgical Service, Harvard University
Summary to resources - Neurosurgery

World Arnold Chiari Malformation Association
April 19, 2007

Hydrocephalus Fact Sheet for Specialists
I.B.I.S. Birth Defects, July 30, 2003
[Ukrainian]
Classification ... Main diagnostic criteria ... Paraclinical diagnosis ... Etiology ... Treatment ... Follow up ... Prevention ... OMIM number ...

Congenital Hydrocephalus
I.B.I.S. Birth Defects, June 30, 2003
[Ukrainian]
A fact sheet for specialists in Ukrainian
Definition ... Clinical features and symptoms ... Diagnosis ... Etiology ... Forms of hydrocephaly ... Prevalence ... Treatment ... Reccurence risk ... Prevention ... OMIM number ...

Arnold-Chiari Malformation
I.B.I.S. Birth Defects, May 8, 2003
[Ukrainian]
A fact sheet for specialists
Types of Arnold-Chiari malformation ... Clinical features and symptoms ... Associated anomalies ... Diagnosis ... Etiology and pathogenesis... Differential diagnosis ... Treatment ... Prevention ... OMIM number ...

FOR PATIENTS AND PARENTS

History of Birth Defects by Rx
NeuralTubeDefect.com, 2011
NeuralTubeDefect.com is an educational website dedicated to providing information about this most common form of birth defect.

Spina Bifida Association of America - since 1973
2007
[Support Group]
"Mission ... to promote the prevention of spina bifida and to enhance the lives of all affected ..."

Association for Spina Bifida and Hydrocephalus
July 23, 2007
[Support Group]
United Kingdom - Ireland. A comprehensive resource.

Spina Bifida and Hydroceophalus Association of Nova Scotia
Spina Bifida and Hydrocephalus Association, 2006
[Support Group]

Resource site for parents
Children and Adults with Spina Bifida and Hydrocephalus, University of Wisconsin. July 11, 2007
[Support Group]
 
Publications - Folic Acid for the Prevention of NTD
Motherisk Organization - Hospital for Sick Children, Toronto, Canada. 2006

Prevención de Defectos del Tubo Neural
International Federation for Spina Bifida and Hydrocephalus (IFSBH)
[Spanish]
El ácido fólico (vitamina B9) es un suplemento simple y barato lo cual reduce la incidencia de DTN en el feto cuando la mujer toma esta vitamina antes de la concepción y durante los primeros 3 meses del embarazo. La dosis recomendada es 0.6 mg por día. Sin embargo, una dieta normal no da este nivel de la vitamina y por lo tanto recomendamos que tome una dosis adicional de 0.4 mg por día ...

Spina bifida - Fact sheet for Parents
I.B.I.S. Birth Defects, 2005
[Ukrainian]
What is spina bifida ... Can it be prevented ... Management of children with spina bifida ... Can spina bifida be diagnosed before birth

Meckel Gruber Syndrome - Fact sheet for Parents
I.B.I.S. Birth Defects, February 5, 2002
[Ukrainian]
What are the main features of the disease ... What are its causes ... Can it be prevented

Congenital Hydrocephalus Fact Sheet for Parents
I.B.I.S. Birth Defects, July 30, 2002
[Ukrainian]
What is hydrocephalus ... Anatomy and physiology ... Diagnosis (various diagnostic methods) ... Treatment ... Care of the affected child

Hydrocephalus Fact Sheet for Parents
I.B.I.S. Birth Defects, July 30, 2002
[Ukrainian]
Physiology of liquor circulation ... Hydrocephaly description ... Diagnosis ... Surgical treatment ... Treatment results and prognosis

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Last Updated: 2014/01/06

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